Serum therapy revisited: animal models of infection and development of passive antibody therapy

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Serum therapy revisited: animal models of infection and development of passive antibody therapy.

In the preantibiotic era, passively administered immune animal sera, or serum therapy, was the primary mode of treatment for many infectious diseases, including diphtheria, tetanus, scarlet fever, pneumococcal pneumonia, and meningitis caused by Neisseria meningitis and Haemophilus influezae (24). Immune sera contained specific antibodies which mediated therapeutic effects by promoting opsoniza...

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ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 1994

ISSN: 0066-4804,1098-6596

DOI: 10.1128/aac.38.8.1695